Author(s)
Radhika Duggal
James R. Xu
David C. Kaelber
Paul C. Bryson
William S. Tierney
Affiliation(s)
Cleveland Clinic Lerner College of Medicine; Case Western Reserve University School of Medicine; The Center for Clinical Informatics Research and Education, The MetroHealth System; Head and Neck Institute, Cleveland Clinic Foundation;
Abstract:
Educational Objective: At the conclusion of this presentation, participants should be able to appreciate the co-existence of psychiatric comorbidities and chronic cough and identify populations at greatest risk.
Objectives: Chronic cough may become a social burden secondary to a false perception of illness by others, contributing to an increased risk for psychiatric diagnoses. To our knowledge, this is the first national study of the incidence and prevalence of psychiatric co-morbidities among patients with chronic cough.
Study Design: Retrospective analysis of TrinetX database from 2012-2023.
Methods: The TriNetX database was queried for patients in the U.S. greater than 18 years of age with a diagnosis of chronic cough. A control cohort of patients without chronic cough was generated. The yearly incidence and prevalence of a psychiatric comorbidity was compared between patients with and without a diagnosis of chronic cough.
Results: We identified approximately 463,000 patients with chronic cough and 34 million patients without. 30.8% of patients with chronic cough had a comorbid mood disorder and 35.5% had a comorbid anxiety disorder. The prevalence of any psychiatric comorbidity increased from 18%-26% in this cohort between 2012 and 2023 while the prevalence in the unaffected cohort only increased from 6%-14%. The average yearly incidence of a new psychiatric comorbidity was 4.4% in individuals with a chronic cough compared to 2.9% in individuals without.