Author(s)
Eshita Singh BS
James C. Wang MD PhD
Hayley Born MD
Allen M. Seiden MD
Affiliation(s)
University of Cincinnati
Abstract:
Educational Objective: At the conclusion of this presentation, the participants should be able to discuss the typical versus possible atypical presentations of esthesioneuroblastoma presenting in the nasal cavity. Objectives: To describe esthesioneuroblastoma originating outside of the superior nasal cavity where the olfactory tissue is normally located. Study Design: Case report. Methods: Esthesioneuroblastoma (ENB) is a rare malignancy of the head and neck, representing only 3% to 6% of all intranasal tumors. ENB typically arises from the neuroepithelium of the olfactory cleft in the superior nasal cavity at the anterior skull base. We present a 39 year old male with intermittent right sided epistaxis, throbbing headache, and maxillary sinus pressure. He reported discomfort that radiated to his right neck with paresthesia of his right upper gingiva. Results: Head and neck CT revealed a partially calcified mass originating in the upper aspect of the right maxillary sinus with extension into the right nasal cavity and nasopharynx measuring 2.8x2.5x2.7cm, with no clear involvement of the olfactory cleft. Patient underwent partial resection with biopsy, which revealed the mass to be attached at the lacrimal bone and infundibulum without visible connection to the olfactory cleft. Pathology was consistent with low grade esthesioneuroblastoma. PET scan showed no evidence of distant metastasis. Conclusions: This is a unique case of esthesioneuroblastoma originating in the maxillary sinus extending into the nasopharynx and nasal cavity without involvement of the olfactory region. Patient reported improvement of headache with no new episodes of epistaxis after resection.